Richard R. Ernst
Richard Robert Ernst (born August 14, 1933) is a Swiss physical chemist and Nobel Laureate.
Born in Winterthur, Switzerland, Ernst was awarded the Nobel Prize in Chemistry in 1991 for his contributions towards the development of Fourier Transform nuclear magnetic resonance spectroscopy while at Varian Associates, Palo Alto and the subsequent development of multi-dimensional NMR techniques.
These underpin applications of NMR both to chemistry (NMR spectroscopy) and to medicine (MRI). He also received the Louisa Gross Horwitz Prize of Columbia University in 1991.After he had finished high school, Ernst started with high expectations and enthusiasm to study chemistry at the famous Swiss Federal Institute of Technology in Zurich
(ETH Zurich).
But he was disappointed by the state of chemistry in the
early 1950s as it was taught at ETH Zurich; the students had to memorize
uncountable facts that even the professors did not understand.
The
physical chemistry lectures did not reveal much insight either, they
were limited just to classical thermodynamics. So, Ernst had to return
to reading in order to get the knowledge he wanted.
He often read the
book "Theoretical Chemistry" by S. Glasstone. In it he learned about the
fundamentals of quantum mechanics, spectroscopy, statistical mechanics,
and statistical thermodynamics.
He studied and served as faculty at ETH Zurich, Switzerland, from which he is now retired.
He is Honorary Doctor of the Technical University of Munich and University of Zurich. Ernst received both his diploma in chemistry (1957) and his Ph.D. in physical chemistry (1962) from ETH Zurich.
Then, from 1963 to 1968 he worked as a research chemist in Palo Alto,
California. In 1966, working with an American colleague, Ernst
discovered that the sensitivity of NMR techniques (hitherto limited to
analysis of only a few nuclei) could be dramatically increased by
replacing the slow, sweeping radio waves traditionally used in NMR
spectroscopy with short, intense pulses. His discovery enabled analysis
of a great many more types of nuclei and smaller amounts of materials.
In 1968 he returned to Switzerland to teach at his alma mater. He was
made assistant professor in 1970 and full professor in 1976.
His second
major contribution to the field of NMR spectroscopy was a technique
that enabled a high-resolution, “two-dimensional” study of larger
molecules than had previously been accessible to NMR.
With Ernst's
refinements, scientists were able to determine the three-dimensional
structure of organic and inorganic compounds and of biological
macromolecules such as proteins; to study the interaction between
biological molecules and other substances such as metal ions, water, and
drugs; to identify chemical species; and to study the rates of chemical
reactions.
Ernst also was credited with many inventions and held several patents in his field.
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